| | | |
| Patient. |
has_property |
Clinical_history, physician |
| Patient. |
has_property |
Cost_of_Treatment, insurer |
| Patient. |
has_property |
Demography, epidemiologist |
| Patient. |
has_property |
Environment |
| Patient. |
has_property |
Family_history, nurse |
| Patient. |
has_property |
Genome, genetic counsellor |
| Patient. |
has_property |
Lifestyle, social context |
| Patient. |
has_property |
Quality_of_life, patient |
| Patient. |
has_property |
Therapeutic_history, pharmacist |
| Patient. |
has_property |
Tissue_samples, pathologist |
| Haemophilia. |
Manage_data |
../concept/data_management. |
| Haemophilia. |
Data_management |
../concept/data_management. |
| Patient_records. |
association |
../concept/data_management. |
| Rostering. |
Hospital |
../concept/Hospital. |
| Health_care. |
association |
../concept/medical_emergency_meeting. |
| Health_care. |
Provied to |
../concept/Patient. |
| Rostering. |
PCT |
../concept/Primary_Care_Trust. |
| Clinical_coding. |
association |
../concept/statistics. |
| Health_care. |
NHS Response to Kennedy Report |
../content/child_care. |
| Clinical_coding. |
ICD_10_&_OPCS_4 |
../content/clinical_coding.htm |
| Dentistry. |
NHS Shakeup 2005 |
../content/dental_shakeup. |
| Dentistry. |
NHS Reorganisation |
../content/dentistry_nhs_2005. |
| Dentistry. |
has_type |
../content/expert_dentist_xp.mdb (.MDB, Access Database) |
| Health_care. |
Hampshire units |
../content/health_care. |
| Grow_your_own_jaw. |
Article |
../content/jaw_regrown. |
| Grow_your_own_jaw. |
graphic_linked |
![../content/jaw_regrown.htm[jaw_titanium.jpg]](image_files/jaw_titanium.jpg) |
| Medicine. |
association |
![../genetics/index.htm [genetics_s.jpg]](image_files/genetics_s.jpg) |
| Haemophilia. |
CJD_prions |
../genetics/prion.htm |
| Rostering. |
Resources |
../management/Resource_Management. |
| Rostering. |
Time |
../management/Time_Management. |
| Haemophilia. |
Employment |
../medicine/agenda_for_change. |
| Haemophilia. |
association |
../medicine/health_care. |
| Haemophilia. |
is_type_of |
../medicine/medicine. |
| Proteomics. |
Knowledge base |
![../proteomics/index.htm [proteomics_s.gif]](image_files/proteomics_s.gif) |
| Haemophilia. |
Type_B |
20% of cases, (lacking in factor IX [9]) |
| Haemophilia. |
Type_A |
80% of cases, (lacking in factor VIII [8]) |
| Rostering. |
e_Rostering |
Staff_cost_savings |
| Haemophilia. |
Data_collection |
Clinical_coding |
| Haemophilia. |
Risk |
Risk_assessment |
| Haemophilia. |
Society |
Haemophilia Society |
| Haemophilia. |
APTT |
Activated Partial Thromboplastin Time |
| Haemophilia. |
CJD, mad cow disease |
Patient_letter (PDF) |
| Rostering. |
e_Rostering |
Secondary Uses Service (SUS) |
| Practice_based_commissioning. |
DH (Dept_of_Health) |
Practice_based_commissioning (PBC)
|
| Agenda_for_change. |
PbR |
Payment_by_Results |
| Agenda_for_change. |
Single_pay_system |
Managing_your_organisation |
| Haemophilia. |
Data_collection_Canada |
Canada |
| Data_protection. |
Details |
More |
| Rostering. |
PBC |
Practice_based_commissioning |
| Rostering. |
e_Rostering |
Shift_patterns |
| Agenda_for_change. |
Training |
NESC, NHS Education for South Central (Wessex) |
| Haemophilia. |
Haemotology |
Haemotology at Southampton |
| Haemophilia. |
Haemophilia_treatment |
Southampton Bookings |
| Practice_based_commissioning. |
NHS_Alliance |
NHS_Brent_PCT |
| Agenda_for_change. |
has_part |
Knowledge and Skills Framework |
| Rostering. |
e_Rostering |
Implementing_e_Rostering |
| Rostering. |
e_Rostering |
Systems |
| Haemophilia. |
Southampton_patient_opinions |
Patient_feedback |
| Haemophilia. |
Aquired_haemophilia |
Myocardial_infarction |
| Haemophilia. |
Southampton |
Southampton University Hospitals |
| Haemophilia. |
../concept/statistics. |
Statistics_about_Haemophilia |
| Health_care. |
Objective |
A greater range of alternative service providers and choice for the patient |
| Beneficence. |
text |
A practitioner should act in the best interest of the patient |
| Data_protection. |
4 |
Accurate and up to date |
| Chemical_pathogen. |
has_type |
Acids, caustic chemicals |
| Malignant_neoplasm. |
has_type |
Adenocarcinoma |
| Benign_neoplasm. |
has_type |
Adenoma |
| Data_protection. |
3 |
Adequate, relevant and not excessive |
| Bridges. |
has_type |
Adhesive |
| Dental_nurse. |
|
Adjust to different work practices of various dentists |
| Practice_based_commissioning. |
PBC_Development_Framework |
Aetna Health Services (UK) in partnership with PwC and the Royal College of General Practitioners
|
| Elderly_care. |
graphic |
 |
| Agenda_for_change. |
description |
Agenda for Change is the single pay system in operation in the NHS. It applies to all directly employed NHS staff with the exception of doctors, dentists and some very senior managers |
| Rostering. |
|
Agenda_for_Change. |
| Health_care. |
association |
Agenda_for_change. |
| Virus. |
description |
Although they reproduce, they can only do so only by entering a host cell and making use of its machinery for replication. Viruses are bits of genetic material, apparentlyderived from their hosts. Thus, as Margulis and Schwartz (1988) put it, the polio and flu viruses are probably more closely related to people, and the tobacco mosaic virus (TMV) to tobacco, than polio and TMV are to each other |
| Material. |
has_type |
Amalgam |
| Medicine. |
has_type |
Anaesthesia |
| Medical_risk_assessment. |
has_part |
Anaesthetic Risks |
| Medicine. |
has_type |
Anatomy. |
| Skeleton. |
association |
Anatomy. |
| Respiratory_system. |
is_type_of |
Anatomy. |
| Anatomy. |
graphic |
 |
| Nematode. |
is_type_of |
Animal. |
| Human. |
is_type_of |
Animal. |
| Bacterium. |
is_type_of |
Animal. |
| Region_of_interest. |
has_property |
Area |
| Dental_nurse. |
|
Assist dentist with four handed dentistry |
| Medical_ethics. |
has_part |
Autonomy. |
| Bacterium. |
graphic |
 |
| Biological_pathogen. |
has_type |
Bacterium. |
| Malignant_neoplasm. |
has_type |
Basal_cell_carcinoma |
| Informed_consent. |
text |
Based on understanding facts and implications |
| Medical_ethics. |
has_part |
Beneficence. |
| Neoplasm. |
has_type |
Benign_neoplasm. |
| Medicine. |
has_type |
Biochemistry. |
| Pathogen. |
has_type |
Biological_pathogen. |
| Infection. |
association |
Biological_pathogen. |
| Fungus. |
is_type_of |
Biological_pathogen. |
| Bacterium. |
is_type_of |
Biological_pathogen. |
| Protozoan. |
is_type_of |
Biological_pathogen. |
| Virus. |
is_type_of |
Biological_pathogen. |
| Prion. |
is_type_of |
Biological_pathogen. |
| Haemophilia. |
Symptons |
Bleeding, Bruising easily, Clotting difficulty |
| Exotoxin. |
example |
Bombardier_beetle |
| Neurosurgery. |
Movie |
brain.mpg (.MPG, Movie) |
| Bridges. |
graphic |
 |
| Restorative. |
has_type |
Bridges. |
| Restorative. |
graphic |
 |
| Cardiology. |
graphic |
cardiac_arrthymia_m.mpg (.MPG, Movie) |
| Medicine. |
has_type |
Cardiology. |
| Cardiovascular. |
is_type_of |
Cardiology. |
| Patient_risks. |
association |
Cardiology. |
| Cardiology. |
has_type |
Cardiothoracic |
| Physiology. |
has_type |
Cardiovascular. |
| Cardiology. |
has_type |
Cardiovascular. |
| Cardiovascular. |
graphic |
 |
| Full_crown. |
has_type |
Cast_metal |
| Practice_based_commissioning. |
PBC_Development_Framework |
Catch on Group
|
| Pathology. |
has_type |
Cellular_pathology |
| Practice_based_commissioning. |
PBC_Development_Framework |
Centre for Innovation in Health Management at Leeds University Business School
|
| Pathogen. |
has_type |
Chemical_pathogen. |
| Treatment. |
has_type |
Chemotherapy |
| Site. |
has_type |
Class I, occlusal surface |
| Site. |
has_type |
Class II, occlusal and proximal surface |
| Site. |
has_type |
Class III, proximal surfaces of anterior teeth |
| Site. |
has_type |
Class IV, proximal surface and incisal edge of anterior teeth |
| Site. |
has_type |
Class V, gingival margin of a buccal aspect of a tooth |
| Maxillofacial. |
has_type |
Cleft lip and palate |
| Health_care. |
association |
Clinical_coding. |
| Data_protection. |
association |
Clinical_coding. |
| Patient_records. |
association |
Clinical_coding. |
| Clinical_coding. |
text |
Coding of operations and diseases together with metadata about the episode of health care they refer to, allows the creation of data for analysis |
| Material. |
has_type |
Composite |
| Veneers. |
has_type |
Composite_veneer |
| Crowns. |
graphic |
 |
| Restorative. |
has_type |
Crowns. |
| Full_crown. |
is_type_of |
Crowns. |
| Clinical_coding. |
association |
Data_protection. |
| Patient_records. |
association |
Data_protection. |
| Dentistry. |
Drill |
dental_drill.wav (Audio) |
| Surgical_dentistry. |
graphic |
 |
| Maxillofacial. |
association |
Dentistry. |
| Dental_nurse. |
association |
Dentistry. |
| Restorative. |
is_type_of |
Dentistry. |
| Surgical_dentistry. |
is_part_of |
Dentistry. |
| Dentistry. |
graphic |
 |
| Maxillofacial. |
has_type |
Dentoalveolar. |
| Surgical_dentistry. |
has_type |
Dentoalveolar. |
| Dental_nurse. |
|
Develop X-rays |
| Health_care. |
Objective |
Devolution of power and resources to the front line to give those professionals who deliver services the freedom to innovate |
| Non_maleficence. |
text |
Do no harm |
| Head_and_neck. |
has_part |
Ear. |
| Ear. |
Movie : Ear |
ear.mpg (.MPG, Movie) |
| Ear. |
graphic |
 |
| Ear. |
graphic |
 |
| Ear. |
graphic |
 |
| Ear. |
graphic |
 |
| Medicine. |
has_type |
Elderly_care. |
| Health_care. |
association |
Elderly_care. |
| Rostering. |
ESR |
Electronic_Staff_Records |
| Medicine. |
has_type |
Embryology. |
| Embryology. |
graphic |
 |
| Embryology. |
graphic |
 |
| Endocrine_system. |
description |
Endocrine glands |
| Physiology. |
has_type |
Endocrine_system. |
| Endocrine_system. |
graphic |
 |
| Dentistry. |
has_type |
Endodontics |
| Toxin. |
has_type |
Endotoxin. |
| Dental_nurse. |
|
Escort patients to surgery |
| Oncology. |
Movie : Ethmoid |
ethmoid_skull.mpg (.MPG, Movie) |
| Toxin. |
has_type |
Exotoxin. |
| Head_and_neck. |
graphic |
 |
| Data_protection. |
1 |
Fairly and lawfully processed |
| Restorative. |
has_type |
Fillings. |
| Material. |
is_part_of |
Fillings. |
| Site. |
is_part_of |
Fillings. |
| Fillings. |
graphic |
 |
| Bridges. |
has_type |
Fixed |
| Bridges. |
has_type |
Fixed_removable |
| Dental_nurse. |
Study |
For dental nursing qualification |
| Physical_pathogen. |
has_type |
Foreign body |
| Dental_nurse. |
Organise |
Forward plan but also be willing to respond to ah hoc requests |
| Crowns. |
has_type |
Full_crown. |
| Biological_pathogen. |
has_type |
Fungus. |
| Fungus. |
graphic |
 |
| Surgery. |
has_type |
General |
| Material. |
has_type |
Glass_ionomer |
| Full_crown. |
has_type |
Gold |
| Restorative. |
has_type |
Grow_your_own_jaw. |
| Restorative. |
has_type |
Grow_your_own_teeth. |
| Medicine. |
has_type |
Haemophilia. |
| Haemophilia. |
Royal_family |
 |
| Agenda_for_change. |
has_part |
Harmonised terms and conditions |
| Maxillofacial. |
has_type |
Head and neck oncology |
| Anatomy. |
has_part |
Head_and_neck. |
| Ear. |
is_part_of |
Head_and_neck. |
| Head_and_neck. |
Movie : Skeleton |
head_shoulders_skeleton.mpg (.MPG, Movie) |
| Surgery. |
graphic |
 |
| Maxillofacial. |
graphic |
 |
| Medicine. |
has_type |
Health_care. |
| Rostering. |
|
Health_Care. |
| Medical_ethics. |
association |
Health_care. |
| Clinical_coding. |
association |
Health_care. |
| Medical_risk_assessment. |
association |
Health_care. |
| Patient_records. |
association |
Health_care. |
| Health_care. |
graphic |
 |
| Patient_risks. |
has_part |
Heart weakness |
| Cardiology. |
Movie |
heart.mpg (.MPG, Movie) |
| Cardiology. |
graphic |
 |
| Dental_nurse. |
Need |
Hep B vaccination |
| Health_care. |
Objective |
High national standards and clear accountability |
| Pathology. |
has_type |
Histology |
| Ear. |
Terms |
http://ctl.augie.edu/perry/ear/hearmech.htm |
| Embryology. |
Carnegie stages |
http://embryo.soad.umich.edu/carnStages/carnStages.html |
| Data_protection. |
ISO_9001 |
http://en.wikipedia.org/wiki/ISO_9001 |
| Health_care. |
ePrints |
http://eprints.soton.ac.uk/ |
| Anatomy. |
Image |
http://human-anatomy.net/index.html |
| Ear. |
Ontology |
http://hyperphysics.phy-astr.gsu.edu/hbase/sound/soucon.html |
| Haemophilia. |
Fragile_X_chromosome |
http://jmg.bmj.com/cgi/content/abstract/31/12/950 |
| Haemophilia. |
Haemophilia_types_source |
http://kidshealth.org/teen/diseases_conditions/blood/hemophilia.html |
| Protozoan. |
Sporozoan |
http://orion1.paisley.ac.uk/courses/Tatner/biomedia/units/prot6.htm |
| Rostering. |
graphic, linked |
![http://shareme.com/screenshot/oriador-staff-rota.html [rostering.gif]](image_files/rostering.gif) |
| Anatomy. |
Movies |
http://splweb.bwh.harvard.edu:8000/pages/images_movies.html#b |
| Haemophilia. |
UKCDO, UK Haemophilia Centre Doctors Organisation |
http://ukhcdo.org/ |
| Haemophilia. |
Centres |
http://ukhcdo.org/HaemophiliaCentres/areacontactslist.htm |
| Haemophilia. |
VisWiki |
http://viswiki.com/en/Haemophilia |
| Elderly_care. |
RICE Institute |
http://www.bath.ac.uk/health/rice/ |
| Head_and_neck. |
Classification |
http://www.bcm.tmc.edu/oto/studs/anat.html |
| Fungus. |
Traps |
http://www.biological-research.com/philip-jacobs%20BRIC/fangorg.htm |
| Bridges. |
graphic, linked |
![http://www.brantacan.co.uk/bridgedefs.htm [bridge_chart.gif]](image_files/bridge_chart.gif) |
| Health_care. |
Common Learning |
http://www.commonlearning.net/contact.asp |
| Ear. |
Anatomy |
http://www.earaces.com/anatomy.htm |
| Mammogram. |
eDiamond Project |
http://www.ediamond.ox.ac.uk/ |
| Health_care. |
ePrints in use |
http://www.eprints.org/ |
| Patient_records. |
Expert Patient Programme |
http://www.expertpatients.nhs.uk/public/default.aspx |
| Informed_consent. |
Freedom to Care |
http://www.freedomtocare.org/page61.htm |
| Surgery. |
is_type_of |
http://www.google.com/Top/Health/Medicine/Surgery/ |
| Haemophilia. |
Definition |
http://www.healthline.com/galecontent/hemophilia-1 |
| Patient_records. |
CAMIS, Clinical_and_management information_system |
http://www.heis.co.uk/camis/camis.htm |
| Patient_records. |
Central_patient_repository |
http://www.heis.co.uk/camis/central_patient_repository.htm |
| Skeleton. |
graphic, linked |
![http://www.infovisual.info/03/011_en.html [skeleton.gif]](image_files/skeleton.gif) |
| Medicine. |
Drawings |
http://www.infovisual.info/03/pano_en.html |
| Productive_ward. |
graphic, linked |
![http://www.institute.nhs.uk/quality_and_value/productive_ward/modules.html [productive_ward.jpg]](image_files/productive_ward.jpg) |
| Pathology. |
Diseases and conditions |
http://www.medicinenet.com/diseases_and_conditions/article.htm |
| Ear. |
Animations, (Quicktime .MOV) |
http://www.neurophys.wisc.edu/h&b/auditory/animation/animationmain.html |
| Haemophilia. |
What_causes_haemophilia? |
http://www.nhlbi.nih.gov/health/dci/Diseases/hemophilia/hemophilia_causes.html |
| Health_care. |
NHS Direct |
http://www.nhsdirect.nhs.uk/ |
| Patient_records. |
Right of access |
http://www.nhsdirect.nhs.uk/articles/article.aspx?ArticleId=1309 |
| Patient_records. |
Self help |
http://www.nhsdirect.nhs.uk/encyclopaedia/ |
| Health_care. |
Medline plus tutorials |
http://www.nlm.nih.gov/medlineplus/tutorial.html |
| Medicine. |
Medical subject browser |
http://www.nlm.nih.gov/mesh/MBrowser.html |
| Practice_based_commissioning. |
Examples |
http://www.pcc.nhs.uk/102 |
| Rostering. |
PBC |
http://www.pcc.nhs.uk/126 |
| Cardiology. |
Embryololgy |
http://www.rchc.rush.edu/rmawebfiles/Embryology.htm#Septationoftheoutflowtract |
| Haemophilia. |
Safe_sedation |
http://www.rcr.ac.uk/publications.aspx?PageID=310&PublicationID=186 |
| Medical_risk_assessment. |
Safe sedation |
http://www.rcr.ac.uk/publications.aspx?PageID=310&PublicationID=186 |
| Virus. |
Image |
http://www.rkm.com.au/imagelibrary/index.html |
| Patient_records. |
Expert Patient Programme, EPP |
http://www.southamptoncitypct.nhs.uk/index.asp?pgid=5205 |
| Elderly_care. |
Southampton NHS |
http://www.suht.nhs.uk/index.cfm?Articleid=219 |
| Toxin. |
definition |
http://www.websters-online-dictionary.org/definition/english/To/Toxin.html |
| Health_care. |
WTCRF Welcome Trust Clinical Research Facility |
http://www.wtcrf.soton.ac.uk/ |
| Person. |
is_instance_of |
Human. |
| Pathogen. |
Affects |
Human. |
| Animal. |
has_type |
Human. |
| Bacterium. |
Predates |
Human. |
| Virus. |
Predates |
Human. |
| Prion. |
Predates |
Human. |
| Practice_based_commissioning. |
PBC_Development_Framework |
Humana Europe in partnership with the NHS Alliance and Dr Foster Intelligence
|
| Clinical_coding. |
Disease Classification |
ICD 10 |
| Haemophilia. |
ICD_10_codes |
III D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism |
| Dental_nurse. |
Prepare |
Impression materials, alginate, putty, wash |
| Health_care. |
Objective |
Increased flexibility for staff to cut across out-moded professional barriers |
| Patient_risks. |
has_part |
Infection. |
| Medical_ethics. |
has_part |
Informed_consent. |
| Biological_pathogen. |
has_type |
Invisible to naked eye |
| Pathogen. |
has_property |
Invokes_organism_response, disease |
| Agenda_for_change. |
has_part |
Job_evaluation |
| Urinary_system. |
Movie : Stone in ureter |
kidney_stone.mpg (.MPG, Movie) |
| Knee_surgery. |
Movie |
knee.mpg (.MPG, Movie) |
| Orthopaedics. |
has_type |
Knee_surgery. |
| Dental_nurse. |
Instruments |
Learn names and recognise about 50 dental instruments |
| Malignant_neoplasm. |
has_type |
Leukemia |
| Benign_neoplasm. |
has_type |
Lipoma |
| Animal. |
is_type_of |
Living_organism |
| Biological_pathogen. |
is_type_of |
Living_organism. |
| Fungus. |
is_type_of |
Living_organism. |
| Virus. |
is_type_of |
Living_organism. |
| Prion. |
is_type_of |
Living_organism. |
| Rostering. |
graphic |
 |
| Respiratory_system. |
Movie |
lung.mpg (.MPG, Movie) |
| Dental_nurse. |
|
Maintain computer and paper records, FP21,FP17, Medical Questionnaire |
| Infection. |
graphic |
 |
| Protozoan. |
graphic |
 |
| Neoplasm. |
has_type |
Malignant_neoplasm. |
| Oncology. |
association |
Mammogram. |
| Region_of_interest. |
is_part_of |
Mammogram. |
| Mammogram. |
graphic |
 |
| Medicine. |
Movie : Man |
man.mpg (.MPG, Movie) |
| Region_of_interest. |
has_property |
Margin |
| Fillings. |
has_type |
Material. |
| Surgery. |
has_type |
Maxillofacial. |
| Dentoalveolar. |
is_type_of |
Maxillofacial. |
| Dentistry. |
association |
Maxillofacial. |
| Medicine. |
.graphic |
 |
| Health_care. |
association |
Medical_ethics. |
| Medicine. |
has_part |
Medical_ethics. |
| Beneficence. |
is_part_of |
Medical_ethics. |
| Non_maleficence. |
is_part_of |
Medical_ethics. |
| Autonomy. |
is_part_of |
Medical_ethics. |
| Informed_consent. |
is_part_of |
Medical_ethics. |
| Health_care. |
association |
Medical_risk_assessment. |
| Patient_risks. |
is_part_of |
Medical_risk_assessment. |
| Rostering. |
|
Medical_workforce |
| Chemical_pathogen. |
has_type |
Medication, drugs, narcotics |
| Elderly_care. |
is_type_of |
Medicine. |
| Embryology. |
is_type_of |
Medicine. |
| Anatomy. |
is_type_of |
Medicine. |
| Biochemistry. |
is_type_of |
Medicine. |
| Physiology. |
is_type_of |
Medicine. |
| Cardiology. |
is_type_of |
Medicine. |
| Oncology. |
is_type_of |
Medicine. |
| Surgery. |
is_type_of |
Medicine. |
| Pathology. |
is_type_of |
Medicine. |
| Paediatrics. |
is_type_of |
Medicine. |
| Orthopaedics. |
is_type_of |
Medicine. |
| Neurosurgery. |
is_type_of |
Medicine. |
| Health_care. |
is_part_of |
Medicine. |
| Medical_ethics. |
is_part_of |
Medicine. |
| Malignant_neoplasm. |
has_type |
Melanoma |
| Pathology. |
has_type |
Molecular_pathology |
| Dental_nurse. |
|
Monitor patients responses |
| Prion. |
Definition |
Natural proteins that have changed in a harmful way, are hard to remove from the food chain and are infectious: |
| Head_and_neck. |
graphic |
 |
| Head_and_neck. |
graphic |
 |
| Head_and_neck. |
graphic |
 |
| Head_and_neck. |
graphic |
 |
| Fungus. |
Predates |
Nematode. |
| Paediatrics. |
has_type |
Neonatal_medicine |
| Oncology. |
has_part |
Neoplasm. |
| Malignant_neoplasm. |
is_type_of |
Neoplasm. |
| Benign_neoplasm. |
is_type_of |
Neoplasm. |
| Toxin. |
has_type |
Nerve effect |
| Neurosurgery. |
graphic |
 |
| Medicine. |
has_type |
Neurosurgery. |
| Grow_your_own_teeth. |
description |
New teeth could soon be grown Living teeth are better for gums than false ones. Technology to grow replacement teeth could mean the end of dentures. Scientists at Kings College London have been awarded £500,000 to help them develop human teeth from stem cells. The company Odontis, set up by the college, hopes to develop its research for tests on humans within two years after successful research on mice. Stem cells, the so-called master cells, would be programmed to develop into teeth and then transplanted into the patients jaw where the gap is. It is thought it would then take two months for the tooth to fully develop. Healthy gums
But it could be five years before the technology is widely available to the general public. On average Britons aged over 50 lose around 12 teeth out of 32. Professor Paul Sharpe is the genetic research scientist behind the technique and head of division of Craniofacial Biology and Biomaterials at the Dental Institute at Kings College.
He said: A key advantage of our technology is that a living tooth can preserve the health of the surrounding tissues much better than artificial prosthesis. Teeth are living, and they are able to respond to a persons bite. They move and in doing so they maintain the health of the surrounding gums and teeth. The cost should not be more than the price of synthetic implants of between £1,500 - £2,000. His project has been awarded £300,000 from the Wellcome Trust, £100,000 from the National Endowment for Science, Technology and the Arts (Nesta) and £100,000 from a business sponsor.
A spokesman for the British Dental Association (BDA) said: The BDA welcomes projects like Odontis and looks forward to seeing further progress in this field |
| Medical_ethics. |
has_part |
Non_maleficence. |
| Data_protection. |
5 |
Not kept for longer than is necessary |
| Data_protection. |
8 |
Not transferred to other countries without adequate protection |
| Pathology. |
has_type |
Nuclear_pathology |
| Medicine. |
has_type |
Oncology. |
| Mammogram. |
association |
Oncology. |
| Treatment. |
is_part_of |
Oncology. |
| Neoplasm. |
is_part_of |
Oncology. |
| Restorative. |
has_type |
Onlays / Inlays |
| Haemophilia. |
Haemophilia_severe |
Only produce 1% of the clotting factor |
| Haemophilia. |
Haemophilia_moderate |
Only produce 2% to 5% of the clotting factor |
| Clinical_coding. |
Operations or Interventions |
OPCS |
| Dentoalveolar. |
graphic |
 |
| Dentistry. |
has_type |
Orthodontics |
| Medicine. |
has_type |
Orthopaedics. |
| Surgery. |
has_type |
Other |
| Medicine. |
has_type |
Paediatrics. |
| Paediatrics. |
has_type |
Paediatric_nephrology |
| Dentistry. |
has_type |
Paedodontics |
| Endotoxin. |
example |
Parasitic wasp |
| Bacterium. |
Predation |
Parasitism. |
| Virus. |
Predation |
Parasitism. |
| Prion. |
Predation |
Parasitism. |
| Pathology. |
has_part |
Pathogen. |
| Human. |
Affected_by |
Pathogen. |
| Biological_pathogen. |
graphic |
 |
| Medicine. |
has_type |
Pathology. |
| Person. |
has_type |
Patient. |
| Patient_records. |
association |
Patient. |
| Patient. |
association |
Patient_records. |
| Health_care. |
association |
Patient_records. |
| Clinical_coding. |
association |
Patient_records. |
| Medical_risk_assessment. |
has_part |
Patient_risks. |
| Infection. |
part_of |
Patient_risks. |
| Dentistry. |
has_type |
Periodontics |
| Haemophilia. |
Procedure |
Peripheral blood stem cell harvesting |
| Patient. |
is_type_of |
Person. |
| Human. |
has_instance |
Person. |
| Pathogen. |
has_type |
Physical_pathogen. |
| Medicine. |
has_type |
Physiology. |
| Respiratory_system. |
is_type_of |
Physiology. |
| Urinary_system. |
is_type_of |
Physiology. |
| Endocrine_system. |
is_type_of |
Physiology. |
| Cardiovascular. |
is_type_of |
Physiology. |
| Dental_nurse. |
|
Place sharps in sharps box |
| Haemophilia. |
Procedure |
Plasma exchange |
| Full_crown. |
has_type |
Porcelain_bonded |
| Full_crown. |
has_type |
Porcelain_jacket |
| Veneers. |
has_type |
Porcelain_veneer |
| Practice_based_commissioning. |
Description |
Practice based commissioning is about involving GP practices and other health and primary care professionals in the commissioning of services |
| Rostering. |
|
Practice_based_commissioning. |
| Parasitism. |
is_type_of |
Predation |
| Dental_nurse. |
Prepare |
Prepare surgery before each patient |
| Biological_pathogen. |
has_type |
Prion. |
| Prion. |
graphic |
 |
| Prion. |
description |
Prions are pathogenic variants of proteins that are naturally produced in nerve cells and certain other cells. The normal healthy prions are referred to as PrPc 0roteinaceous infectious particle and so should properly only be applied to the pathogenic variants. RNA that codes for PrPc is produced in the nucleus and exits via the nuclear pore. The RNA then passes along ribosomes attached to the rER. PrPc is formed in the rER and then progresses up through the Golgi. At the upper face of the Golgi, vesicles containing PrPc bud off and travel to the cell surface. Here, they fuse with the cell membrane and so discharge their cargo at PrPc. By this means, the cellular proteins come to sit on the exterior of the cell.
PrPc encounter rogue (purple) prions. These are termed PrPsc (sc stands for scrapie, the prion disease of sheep). The rogue prions seem to force the normal proteins to change shape. Both types of protein, the PrPc and their corresponding prions, are the same chemical - just different shapes. It is this shape-flipping which is equivalent to the transmission of infection. Such a conformational shift or flip could happen at the cell surface or in caveolae (one is shown as a small invagination in the cell membrane). Residual PrPc might continue to be flipped by contact with the rogue confomations for some time in these vesicles.
Prions polymerise, finally appearing as purple fibrils in the picture at P. PrPsc is resistant to degradation by the enzymes contained in the lysosomes that are seen floating nearby. Consequently, PrPsc accumulates in the cell. PrPsc vesicles may also travel to the Golgi and intercept PrPc that is being processed there. In this way, PrPc particles could be switched to the rogue form before they reach the surface of the cell. By such mechanisms, PrPc might be switched to PrPsc at various points in and on the cell. It must be emphasised that prion biology is not fully understood and much remains speculative |
| Data_protection. |
2 |
Processed for limited purposes |
| Data_protection. |
6 |
Processed in line with your rights |
| Haemophilia. |
Haemophilia_mild |
Produce 6% to 50%of the clotting factor |
| Rostering. |
|
Productive_Ward. |
| Dentistry. |
has_type |
Prosthodontics |
| Biochemistry. |
has_type |
Proteomics. |
| Proteomics. |
graphic |
 |
| Biological_pathogen. |
has_type |
Protozoan. |
| Physical_pathogen. |
has_type |
Radiation |
| Treatment. |
has_type |
Radiotherapy |
| Haemophilia. |
Procedure |
Red cell exchange |
| Mammogram. |
has_part |
Region_of_interest. |
| Bridges. |
has_type |
Removable |
| Dental_nurse. |
|
Report volunteered information |
| Proteomics. |
is_type_of |
Research_area |
| Patient_risks. |
has_part |
Respiratory condition |
| Patient_risks. |
graphic |
 |
| Physiology. |
has_type |
Respiratory_system. |
| Patient_risks. |
association |
Respiratory_system. |
| Respiratory_system. |
graphic |
 |
| Dental_nurse. |
Prepare |
Restorative materials, glass ionomer, cement, amalgam |
| Dentistry. |
has_type |
Restorative. |
| Crowns. |
is_type_of |
Restorative. |
| Veneers. |
is_type_of |
Restorative. |
| Bridges. |
is_type_of |
Restorative. |
| Fillings. |
is_type_of |
Restorative. |
| Grow_your_own_jaw. |
is_part_of |
Restorative. |
| Grow_your_own_teeth. |
is_part_of |
Restorative. |
| Medical_risk_assessment. |
graphic |
 |
| Agenda_for_change. |
association |
Rostering. |
| Practice_based_commissioning. |
association |
Rostering. |
| Productive_ward. |
association |
Rostering. |
| Data_protection. |
7 |
Secure |
| Region_of_interest. |
has_property |
Shape |
| Rostering. |
|
Shift_pattern |
| Fillings. |
has_type |
Site. |
| Anatomy. |
association |
Skeleton. |
| Health_care. |
association |
Social_Care_Services |
| Endotoxin. |
example |
Spider |
| Exotoxin. |
example |
Spitting_cobra |
| Malignant_neoplasm. |
has_type |
Squamous_cell_carcinoma |
| Dental_nurse. |
Instruments |
Sterilize instruments by autoclave or ultrasonic bath |
| Dental_nurse. |
|
Supply suction |
| Medicine. |
has_type |
Surgery. |
| Treatment. |
has_type |
Surgery. |
| Maxillofacial. |
is_type_of |
Surgery. |
| Medical_risk_assessment. |
has_part |
Surgical Risks |
| Dentistry. |
has_type |
Surgical_dentistry. |
| Dentoalveolar. |
is_part_of |
Surgical_dentistry. |
| Grow_your_own_teeth. |
graphic |
 |
| Material. |
has_type |
Temporary_cement |
| Autonomy. |
text |
The patient has the right to refuse or choose their treatment |
| Haemophilia. |
Procedure |
Therapeutic leucapheresis |
| Haemophilia. |
Procedure |
Therapeutic platelet apheresis |
| Crowns. |
graphic |
Three_quarter |
| Dentoalveolar. |
Movie |
tooth.mpg (.MPG, Movie) |
| Grow_your_own_teeth. |
Movie |
tooth2.mpg (.MPG, Movie) |
| Skeleton. |
Movie |
torso_skeleton.mpg (.MPG, Movie) |
| Toxin. |
Related concept |
Toxic, as used in Conservation ontology |
| Exotoxin. |
is_type_of |
Toxin. |
| Endotoxin. |
is_type_of |
Toxin. |
| Chemical_pathogen. |
has_type |
Toxin. |
| Oncology. |
has_part |
Treatment. |
| Practice_based_commissioning. |
PBC_Development_Framework |
Tribal Group in partnership with Quest4Quality |
| Physiology. |
has_type |
Urinary_system. |
| Urinary_system. |
graphic |
 |
| Restorative. |
has_type |
Veneers. |
| Biological_pathogen. |
has_type |
Virus. |
| Virus. |
graphic |
 |
| Rostering. |
|
Working_practice |
472 total tuples